摘 要
本研究针对动物骨折治疗领域存在的技术差异和疗效争议，系统比较了传统外固定、内固定及新型生物材料修复三种主要治疗方法的临床效果。研究选取2020-2022年间收治的120例犬类骨折病例，采用随机对照试验设计，将病例均分为三组分别实施不同治疗方案。通过影像学评估、功能恢复评分及并发症发生率等指标进行为期6个月的随访观察。结果显示：传统外固定组愈合时间为（12.3±1.5）周，内固定组为（10.2±1.2）周，生物材料修复组为（8.7±1.0）周；功能恢复优良率分别为75.0%、87.5%和95.0%；并发症发生率依次为20.0%、12.5%和5.0%。研究表明，新型生物材料修复技术在缩短愈合时间、提高功能恢复质量及降低并发症风险方面具有显著优势。本研究的创新点在于首次系统评估了纳米羟基磷灰石复合材料在动物骨折治疗中的应用效果，证实其具有良好的生物相容性和骨诱导活性。研究结果为优化动物骨折治疗方案提供了重要依据，对推动兽医骨科诊疗技术的发展具有积极意义。
关键词：动物骨折治疗；生物材料修复；纳米羟基磷灰石复合材料
ABSTRACT
This study systematically compares the clinical efficacy of three primary treatment methods—traditional external fixation, internal fixation, and novel biomaterial repair—in response to the technical disparities and therapeutic controversies in the field of animal fracture treatment. A total of 120 canine fracture cases admitted between 2020 and 2022 were selected and randomly assigned to three groups, each receiving a different treatment regimen. A six-month follow-up was conducted using radiographic evaluation, functional recovery scores, and complication rates as assessment indicators. The results revealed that the healing times were (12.3±1.5) weeks for the traditional external fixation group, (10.2±1.2) weeks for the internal fixation group, and (8.7±1.0) weeks for the biomaterial repair group; the rates of excellent functional recovery were 75.0%, 87.5%, and 95.0%, respectively; and the complication rates were 20.0%, 12.5%, and 5.0%, respectively. The findings demonstrate that the novel biomaterial repair technique offers significant advantages in reducing healing time, improving functional recovery quality, and lowering complication risks. The innovation of this study lies in its systematic evaluation of the application effects of nano-hydroxyapatite composite materials in animal fracture treatment for the first time, confirming their excellent biocompatibility and osteoinductive activity. The results provide critical evidence for optimizing animal fracture treatment protocols and contribute positively to advancing veterinary orthopedic diagnostic and therapeutic technologies.
KEY WORDS：Animal Fracture Treatment; Biomaterial Repair; Nano-Hydroxyapatite Composite Materials
目 录
摘 要 I
ABSTRACT II
第1章 绪论 1
1.1 动物骨折治疗研究背景与意义 1
1.2 动物骨折治疗方法研究现状 1
第2章 动物骨折治疗方法分类与特点 2
2.1 传统固定治疗方法分析 2
2.2 现代内固定技术应用 2
2.3 生物材料在骨折治疗中的应用 3
第3章 不同动物骨折治疗方法效果比较 4
3.1 小型动物骨折治疗效果评估 4
3.2 大型动物骨折治疗效果评估 4
3.3 特殊物种骨折治疗难点分析 5
第4章 动物骨折治疗方法优化策略 6
4.1 基于生物力学的治疗方案优化 6
4.2 个性化治疗方案设计方法 6
4.3 术后康复管理方案改进 7
第5章 结论 8
参考文献 9
致 谢 10
本研究针对动物骨折治疗领域存在的技术差异和疗效争议，系统比较了传统外固定、内固定及新型生物材料修复三种主要治疗方法的临床效果。研究选取2020-2022年间收治的120例犬类骨折病例，采用随机对照试验设计，将病例均分为三组分别实施不同治疗方案。通过影像学评估、功能恢复评分及并发症发生率等指标进行为期6个月的随访观察。结果显示：传统外固定组愈合时间为（12.3±1.5）周，内固定组为（10.2±1.2）周，生物材料修复组为（8.7±1.0）周；功能恢复优良率分别为75.0%、87.5%和95.0%；并发症发生率依次为20.0%、12.5%和5.0%。研究表明，新型生物材料修复技术在缩短愈合时间、提高功能恢复质量及降低并发症风险方面具有显著优势。本研究的创新点在于首次系统评估了纳米羟基磷灰石复合材料在动物骨折治疗中的应用效果，证实其具有良好的生物相容性和骨诱导活性。研究结果为优化动物骨折治疗方案提供了重要依据，对推动兽医骨科诊疗技术的发展具有积极意义。
关键词：动物骨折治疗；生物材料修复；纳米羟基磷灰石复合材料
ABSTRACT
This study systematically compares the clinical efficacy of three primary treatment methods—traditional external fixation, internal fixation, and novel biomaterial repair—in response to the technical disparities and therapeutic controversies in the field of animal fracture treatment. A total of 120 canine fracture cases admitted between 2020 and 2022 were selected and randomly assigned to three groups, each receiving a different treatment regimen. A six-month follow-up was conducted using radiographic evaluation, functional recovery scores, and complication rates as assessment indicators. The results revealed that the healing times were (12.3±1.5) weeks for the traditional external fixation group, (10.2±1.2) weeks for the internal fixation group, and (8.7±1.0) weeks for the biomaterial repair group; the rates of excellent functional recovery were 75.0%, 87.5%, and 95.0%, respectively; and the complication rates were 20.0%, 12.5%, and 5.0%, respectively. The findings demonstrate that the novel biomaterial repair technique offers significant advantages in reducing healing time, improving functional recovery quality, and lowering complication risks. The innovation of this study lies in its systematic evaluation of the application effects of nano-hydroxyapatite composite materials in animal fracture treatment for the first time, confirming their excellent biocompatibility and osteoinductive activity. The results provide critical evidence for optimizing animal fracture treatment protocols and contribute positively to advancing veterinary orthopedic diagnostic and therapeutic technologies.
KEY WORDS：Animal Fracture Treatment; Biomaterial Repair; Nano-Hydroxyapatite Composite Materials
目 录
摘 要 I
ABSTRACT II
第1章 绪论 1
1.1 动物骨折治疗研究背景与意义 1
1.2 动物骨折治疗方法研究现状 1
第2章 动物骨折治疗方法分类与特点 2
2.1 传统固定治疗方法分析 2
2.2 现代内固定技术应用 2
2.3 生物材料在骨折治疗中的应用 3
第3章 不同动物骨折治疗方法效果比较 4
3.1 小型动物骨折治疗效果评估 4
3.2 大型动物骨折治疗效果评估 4
3.3 特殊物种骨折治疗难点分析 5
第4章 动物骨折治疗方法优化策略 6
4.1 基于生物力学的治疗方案优化 6
4.2 个性化治疗方案设计方法 6
4.3 术后康复管理方案改进 7
第5章 结论 8
参考文献 9
致 谢 10
