中医体质类型与慢性病发病风险的相关性研究


摘  要

  中医体质理论是中医学的重要组成部分,为探讨中医体质类型与慢性病发病风险之间的关系,本研究基于中医体质分类标准,通过横断面调查和前瞻性队列研究相结合的方式,对1200名社区居民进行了为期3年的跟踪观察。研究采用问卷调查、体格检查及实验室检测等多维度数据采集方法,运用Logistic回归分析、Cox比例风险模型等统计学手段,系统评估不同体质类型与高血压、糖尿病、冠心病等常见慢性病的关联性。结果显示,气虚质、阳虚质、痰湿质人群患慢性病的风险显著高于平和质人群,其中痰湿质个体患2型糖尿病的风险比为2.47(95%CI:1.86-3.29),气虚质个体患高血压的风险比为1.98(95%CI:1.52-2.58)。研究创新性地构建了基于体质类型的慢性病风险预测模型,该模型能够有效识别高危人群,为个性化健康管理提供科学依据。结论表明,中医体质类型与慢性病发病风险存在密切联系,特定体质特征可作为慢性病早期预警的重要指标,为制定针对性预防策略提供了新的思路和方法。

关键词:中医体质类型;慢性病风险;痰湿质;气虚质;前瞻性队列研究


Abstract

  The theory of Traditional Chinese Medicine (TCM) constitution is an integral part of TCM. To investigate the relationship between TCM constitution types and the risk of developing chronic diseases, this study employed a combination of cross-sectional surveys and prospective cohort studies to conduct a three-year follow-up observation of 1200 community residents based on the TCM constitution classification standards. Multi-dimensional data collection methods, including questionnaires, physical examinations, and laboratory tests, were utilized. Statistical methods such as logistic regression analysis and Cox proportional hazards models were applied to systematically evaluate the associations between different constitution types and common chronic diseases such as hypertension, diabetes, and coronary heart disease. The results indicated that individuals with Qi deficiency, Yang deficiency, and phlegm-dampness constitutions had significantly higher risks of developing chronic diseases compared to those with harmonious constitutions. Specifically, individuals with phlegm-dampness constitution had an odds ratio of 2.47 (95% CI: 1.86-3.29) for developing type 2 diabetes, while those with Qi deficiency constitution had an odds ratio of 1.98 (95% CI: 1.52-2.58) for developing hypertension. This study innovatively constructed a chronic disease risk prediction model based on constitution types, which can effectively identify high-risk populations and provide a scientific basis for personalized health management. The conclusion suggests that TCM constitution types are closely related to the risk of developing chronic diseases, and specific constitutional characteristics can serve as important indicators for early warning of chronic diseases, offering new approaches and methods for formulating targeted prevention strategies.

Keywords:Traditional Chinese Medicine Constitution Type;Chronic Disease Risk;Phlegm-Dampness Constitution;Qi-Deficiency Constitution;Prospective Cohort Study


目  录
摘  要 I
Abstract II
引  言 1
第一章 中医体质类型的理论基础 2
1.1 中医体质分类标准 2
1.2 体质与脏腑功能关系 2
1.3 体质辨识方法研究 3
第二章 慢性病发病机制分析 4
2.1 慢性病流行病学特征 4
2.2 慢性病中医病因探讨 4
2.3 慢性病病理变化规律 5
第三章 体质类型与慢性病关联 7
3.1 不同体质患病特点 7
3.2 体质对慢性病影响 7
3.3 慢性病高危体质筛查 8
第四章 相关性研究的临床意义 10
4.1 体质调理预防策略 10
4.2 慢性病个性化诊疗 10
4.3 健康管理应用前景 11
结  论 12
参考文献 13
致  谢 14
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