摘 要
首先，本文从中药复方的补钙效果、对骨代谢的影响、抗骨吸收作用以及临床应用案例分析等方面，系统地阐述了中药复方在老年骨质疏松症治疗中的作用。研究发现，中药复方能够显著提高血清钙水平，促进骨形成，抑制骨吸收，从而改善骨质疏松症患者的骨密度和骨质量。进一步地，本研究深入探讨了中药复方的作用机制。结果表明，中药复方通过影响骨代谢相关细胞，如成骨细胞和破骨细胞，调节其增殖、分化和凋亡，从而促进骨形成和抑制骨吸收。研究结果显示，中药复方的不良反应发生率低，且多数为轻微和可逆的，表明其在临床应用中具有较好的安全性。同时，本研究还探讨了中药复方与其他药物的相互作用，为临床合理用药提供了参考。
关键词：中药复方；老年骨质疏松症；治疗作用；作用机制；安全性评价
STUDY ON THE THERAPEUTIC EFFECT AND MECHANISM OF CHINESE HERBAL COMPOUND ON SENILE OSTEOPOROSIS
ABSTRACT
Firstly, this paper systematically expounds the role of TCM compounds in the treatment of senile osteoporosis from the aspects of calcium supplementation effect, bone me tabolism effect, anti-bone resorption effect and clinical case analysis. Studies have found that Chinese herbal compounds can significantly increase serum calcium levels, promote bone formation, inhibit bone resorption, and thus improve bone density and bone quality in osteoporosis patients. Further, this study explored the mechanism of action of Chinese medicine compound. The results showed that TCM compounds could regulate the proliferation, differentiation and apoptosis of bone me tabolisation-related cells, such as osteoblasts and osteoclasts, thereby promoting bone formation and inhibiting bone resorption. The results showed that the incidence of adverse reactions of TCM compounds was low, and most of them were mild and reversible, indicating that it had a good safety in clinical application. At the same time, this study also discussed the interaction between TCM compounds and other drugs, and provided a reference for clinical rational drug use.
KEY WORDS：TCM compound; Senile osteoporosis; Therapeutic effect; Mechanism of action; Safety evaluation
目 录
摘 要 I
ABSTRACT II
第1章 引言 2
第2章 中药复方的治疗作用 3
2.1 中药复方的补钙效果 3
2.2 中药复方对骨代谢的影响 3
2.3 中药复方的抗骨吸收作用 3
2.4 中药复方的临床应用案例分析 4
第3章 中药复方的治疗机制探讨 5
3.1 对骨代谢相关细胞的影响 5
3.2 内分泌调节作用 5
3.3 抗氧化与抗炎作用 5
3.4 信号转导途径的调控 6
第4章 中药复方治疗老年骨质疏松症的安全性评价 7
4.1 不良反应的监测与记录 7
4.2 安全性评价指标的建立 7
4.3 与其他药物的相互作用 7
4.4 药物代谢动力学研究 8
第5章 结论 9
参考文献 10
致 谢 11
