摘要
妊娠期急性胰腺炎是一种少见但严重的产科急症，其发病机制复杂且诊疗难度较高，对母儿健康构成重大威胁为探讨妊娠期急性胰腺炎的临床特征及多学科协作诊疗模式的效果，本研究回顾性分析了某三甲医院2015年至2022年间收治的28例妊娠期急性胰腺炎患者的临床资料，包括病因、病情严重程度、治疗方案及母婴结局通过多学科团队（MDT）协作，制定个体化治疗策略，结果显示，胆石症是主要诱因（占64.3%），其次是高脂血症和特发性因素所有患者均接受保守治疗，其中12例重症患者在多学科干预下成功控制病情，仅1例因早产导致新生儿死亡随访发现，经及时诊断与综合管理，大部分患者预后良好本研究证实，多学科协作诊疗可显著提高妊娠期急性胰腺炎的诊治水平，为优化临床路径提供了重要参考，同时强调早期识别和精准干预的重要性，为改善母婴结局贡献了新思路关键词：妊娠期急性胰腺炎；多学科协作诊疗；胆石症；高脂血症；母婴结局
Multidisciplinary Diagnosis and Treatment of Acute Pancreatitis During Pregnancy: A Case Analysis
Abstract
Acute pancreatitis during pregnancy is a rare but severe obstetric emergency with complex pathogenesis and high diagnostic and therapeutic challenges, posing significant threats to maternal and fetal health. To investigate the clinical characteristics of acute pancreatitis in pregnancy and the effectiveness of a multidisciplinary team (MDT) collaborative treatment model, this study conducted a retrospective analysis of clinical data from 28 patients with acute pancreatitis during pregnancy admitted to a tertiary hospital between 2015 and 2022. The data included etiology, disease severity, treatment strategies, and maternal-fetal outcomes. Through MDT collaboration, individualized treatment plans were developed, revealing that gallstone disease was the primary cause (64.3%), followed by hyperlipidemia and idiopathic factors. All patients received conservative treatment, and among the 12 severe cases, the condition was successfully controlled under multidisciplinary intervention, with only one neonatal death due to preterm birth. Follow-up indicated that most patients achieved favorable outcomes when timely diagnosis and comprehensive management were implemented. This study confirms that MDT-based collaborative care significantly enhances the diagnostic and therapeutic levels for acute pancreatitis during pregnancy, providing critical reference for optimizing clinical pathways. It also underscores the importance of early identification and precise intervention, offering new insights into improving maternal and fetal outcomes.
Keywords: Acute Pancreatitis In Pregnancy; Multidisciplinary Team Collaboration; Gallstone Disease; Hyperlipidemia; Maternal And Fetal Outcomes
目录
摘要 I
Abstract II
引言 1
1 妊娠期急性胰腺炎的临床特征分析 1
1.1 病例资料与发病特点 1
1.2 临床表现与诊断难点 2
1.3 特殊人群的风险评估 2
2 多学科协作诊疗模式探讨 2
2.1 急诊处理与初步评估 3
2.2 内科干预与病情控制 3
2.3 产科参与与母婴安全 3
3 治疗策略与个体化方案制定 4
3.1 药物治疗的选择与优化 4
3.2 手术干预的适应症与时机 4
3.3 营养支持与康复管理 5
4 预后评估与长期随访研究 5
4.1 母体预后影响因素分析 5
4.2 新生儿结局与风险防控 6
4.3 随访体系的建立与完善 6
结论 7
参考文献 8
致谢 9
