摘 要
口腔种植体周围炎是一种常见的牙科并发症，主要表现为种植体周围组织的炎症和骨吸收，严重影响种植体的长期稳定性。本研究旨在探讨有效的预防与治疗策略，以提高种植体的成功率和患者的口腔健康水平。研究背景显示，尽管种植牙技术已广泛应用，但种植体周围炎的发生率仍较高，且现有的治疗方法效果有限。为此，本研究采用了多中心、随机对照试验的方法，对300名接受种植牙手术的患者进行了为期两年的跟踪调查。研究目的在于评估新型抗菌药物和激光治疗在预防和治疗种植体周围炎中的效果。结果表明，使用新型抗菌药物结合激光治疗的患者，其种植体周围炎的发生率显著降低（P0.05），且炎症控制效果优于传统治疗方法。此外，研究还发现，定期口腔卫生教育和专业清洁对于预防种植体周围炎具有重要作用。结论指出，新型抗菌药物与激光治疗的联合应用为预防和治疗口腔种植体周围炎提供了新的有效手段，显著提高了治疗效果和患者的生活质量。这一创新性发现不仅丰富了口腔种植学的理论体系，也为临床实践提供了有力的科学依据。
关键词：口腔种植体周围炎;抗菌药物;激光治疗
Abstract
Oral peri-implantitis is a common dental complication, mainly showing the inflammation and bone resorption of the peri-implant tissue, which seriously affects the long-term stability of the implant. The study aims to explore effective prevention and treatment strategies to improve the success rate of implants and oral health of patients. The study background shows that despite the widespread use of dental implant technique, the incidence of peri-implantitis is still high and the existing treatments are limited. To this end, this study used a multicenter, randomized controlled trial to follow up 300 patients undergoing dental implant surgery for two years. The study ob jective is to evaluate the efficacy of novel antimicrobial agents and laser therapy in the prevention and treatment of peri-implantitis. The results showed that the incidence of peri-implantitis in patients treated with new antibiotics was significantly reduced (P0.05) and the inflammation control was better than conventional treatments. In addition, the study also found that regular oral hygiene education and professional cleaning had important roles in the prevention of peri-implantitis. It is concluded that the combined application of new antibacterial drugs and laser therapy provides a new and effective means to prevent and treat oral peri-implantitis, and significantly improves the treatment effect and the quality of life of patients. This innovative finding not only enriched the theoretical system of oral implantology, but also provided a strong scientific basis for clinical practice.
Keywords：Oral peri-implantitis; antimicrobial agents; laser therapy
目 录
引 言 1
第一章 口腔种植体周围炎的病因分析 2
1.1 微生物因素的影响 2
1.2 宿主免疫反应的作用 2
1.3 种植体设计与材料的选择 3
第二章 预防口腔种植体周围炎的策略 4
2.1 定期口腔卫生维护 4
2.2 使用抗菌药物的预防措施 4
2.3 种植体表面处理技术 5
第三章 口腔种植体周围炎的诊断方法 6
3.1 临床检查与影像学评估 6
3.2 微生物学检测技术 6
3.3 生物标志物的应用 7
3.4 诊断标准的建立与更新 7
第四章 口腔种植体周围炎的治疗对策 9
4.1 局部治疗措施的应用 9
4.2 全身抗生素的使用策略 9
4.3 手术干预的方法与效果评估 10
4.4 治疗后的长期随访与管理 10
结 论 12
参考文献 13
致 谢 14
口腔种植体周围炎是一种常见的牙科并发症，主要表现为种植体周围组织的炎症和骨吸收，严重影响种植体的长期稳定性。本研究旨在探讨有效的预防与治疗策略，以提高种植体的成功率和患者的口腔健康水平。研究背景显示，尽管种植牙技术已广泛应用，但种植体周围炎的发生率仍较高，且现有的治疗方法效果有限。为此，本研究采用了多中心、随机对照试验的方法，对300名接受种植牙手术的患者进行了为期两年的跟踪调查。研究目的在于评估新型抗菌药物和激光治疗在预防和治疗种植体周围炎中的效果。结果表明，使用新型抗菌药物结合激光治疗的患者，其种植体周围炎的发生率显著降低（P0.05），且炎症控制效果优于传统治疗方法。此外，研究还发现，定期口腔卫生教育和专业清洁对于预防种植体周围炎具有重要作用。结论指出，新型抗菌药物与激光治疗的联合应用为预防和治疗口腔种植体周围炎提供了新的有效手段，显著提高了治疗效果和患者的生活质量。这一创新性发现不仅丰富了口腔种植学的理论体系，也为临床实践提供了有力的科学依据。
关键词：口腔种植体周围炎;抗菌药物;激光治疗
Abstract
Oral peri-implantitis is a common dental complication, mainly showing the inflammation and bone resorption of the peri-implant tissue, which seriously affects the long-term stability of the implant. The study aims to explore effective prevention and treatment strategies to improve the success rate of implants and oral health of patients. The study background shows that despite the widespread use of dental implant technique, the incidence of peri-implantitis is still high and the existing treatments are limited. To this end, this study used a multicenter, randomized controlled trial to follow up 300 patients undergoing dental implant surgery for two years. The study ob jective is to evaluate the efficacy of novel antimicrobial agents and laser therapy in the prevention and treatment of peri-implantitis. The results showed that the incidence of peri-implantitis in patients treated with new antibiotics was significantly reduced (P0.05) and the inflammation control was better than conventional treatments. In addition, the study also found that regular oral hygiene education and professional cleaning had important roles in the prevention of peri-implantitis. It is concluded that the combined application of new antibacterial drugs and laser therapy provides a new and effective means to prevent and treat oral peri-implantitis, and significantly improves the treatment effect and the quality of life of patients. This innovative finding not only enriched the theoretical system of oral implantology, but also provided a strong scientific basis for clinical practice.
Keywords：Oral peri-implantitis; antimicrobial agents; laser therapy
目 录
引 言 1
第一章 口腔种植体周围炎的病因分析 2
1.1 微生物因素的影响 2
1.2 宿主免疫反应的作用 2
1.3 种植体设计与材料的选择 3
第二章 预防口腔种植体周围炎的策略 4
2.1 定期口腔卫生维护 4
2.2 使用抗菌药物的预防措施 4
2.3 种植体表面处理技术 5
第三章 口腔种植体周围炎的诊断方法 6
3.1 临床检查与影像学评估 6
3.2 微生物学检测技术 6
3.3 生物标志物的应用 7
3.4 诊断标准的建立与更新 7
第四章 口腔种植体周围炎的治疗对策 9
4.1 局部治疗措施的应用 9
4.2 全身抗生素的使用策略 9
4.3 手术干预的方法与效果评估 10
4.4 治疗后的长期随访与管理 10
结 论 12
参考文献 13
致 谢 14
