摘 要
中国是脑卒中高发国家之一,预防和治疗脑卒中已成为临床重要课题之一。中风后神经保护药物的研究和开发成为各国的研究热点。本文主要从中风后神经保护药物的概述、研究现状和发展趋势以及临床应用这几个方面进行探讨和分析,以期深入了解中风后神经保护药物的研究现状及发展趋势。在中风后神经保护药物概述部分,阐述了中风后神经保护药物的定义和作用,以及脑卒中的现状和对神经保护药物的需求。在中风后神经保护药物的发展趋势方面,本文提出了新型神经营养因子、靶向氧化应激和自由基的新型神经保护药物和天然产物在神经保护药物中的应用展望。最后,本文探讨了已上市的神经保护药物及其临床应用,以及应用中存在的问题和不足,并对未来的发展方向与期望进行了探讨。总之,本文旨在对中风后神经保护药物的研究现状、发展趋势和临床应用进行探讨,以期进一步提高我国脑卒中的治疗水平和预防工作的能力。
关键词:中风;神经保护;药物;研究
Abstract
China is one of the countries with a high incidence of stroke, and the prevention and treatment of stroke has become one of the important clinical topics. The research and development of neuroprotective drugs after stroke has become a research hotspot in various countries. This article mainly discusses and analyzes the overview, research status and development trends, as well as clinical applications of post stroke neuroprotective drugs, in order to gain a deeper understanding of the research status and development trends of post stroke neuroprotective drugs. In the overview section of post stroke neuroprotective drugs, the definition and role of post stroke neuroprotective drugs are elaborated, as well as the current situation of stroke and the demand for neuroprotective drugs. In terms of the development trend of neuroprotective drugs after stroke, this paper proposed the application prospects of new neurotrophin, new neuroprotective drugs targeting oxidative stress and free radicals, and natural products in neuroprotective drugs. Finally, this article explores the listed neuroprotective drugs and their clinical applications, as well as the problems and shortcomings in their application, and explores the future development direction and expectations. In summary, this article aims to explore the research status, development trends, and clinical applications of neuroprotective drugs after stroke, in order to further improve the treatment level and prevention ability of stroke in China.
Keywords:Stroke; Neuroprotection; Medications; Research
目录
摘 要 1
Abstract 2
引言 3
一、脑卒中后神经保护剂的研究概况 4
(一)脑卒中后神经保护剂的概念及功能 4
(二)我国中风患者的状况及对神经保护剂的需要 4
二、脑卒中后神经保护剂的临床应用 5
(一) NGF对缺血性脑卒中的影响及应用 5
(二)缺血性脑卒中的氧化应激、自由基损害及神经保护剂 6
(三)具有神经保护性作用的中药提取液 6
三、脑卒中后神经保护剂的开发动向 7
(一)一种新的神经生长因子,并展望了它的用途 7
(二)新的以氧化压力和自由基为靶点的神经保护剂 7
(三)用于神经保护剂的天然产物前景 8
四、脑卒中后的神经保护剂在临床上的运用 8
(一)已上市的神经保护剂和临床使用情况 8
(二)实际运用中的问题与缺陷 9
(三)今后的发展趋势和展望 10
结论 10
参考文献 12